5-Pyrimidinecarboxaldehyde, 2-amino- (9CI) - Names and Identifiers
5-Pyrimidinecarboxaldehyde, 2-amino- (9CI) - Physico-chemical Properties
Molecular Formula | C5H5N3O
|
Molar Mass | 123.11 |
Density | 1.370±0.06 g/cm3(Predicted) |
Melting Point | 209-214°C |
Boling Point | 372.7±34.0 °C(Predicted) |
Flash Point | 179.173°C |
Vapor Presure | 0mmHg at 25°C |
Appearance | White to yellow to brown powder or solid |
pKa | 1.99±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.667 |
MDL | MFCD03701714 |
5-Pyrimidinecarboxaldehyde, 2-amino- (9CI) - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R43 - May cause sensitization by skin contact
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S36/37 - Wear suitable protective clothing and gloves.
S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
WGK Germany | 3 |
HS Code | 29339900 |
Hazard Class | IRRITANT |
5-Pyrimidinecarboxaldehyde, 2-amino- (9CI) - Introduction
2-Amino-5-pyrimidine formaldehyde is an organic compound with the following properties:
1. appearance: 2-amino -5-pyrimidine formaldehyde is colorless or light yellow crystalline solid.
2. solubility: soluble in water and some organic solvents, such as ethanol and ether.
3. chemical properties: 2-amino -5-pyrimidine formaldehyde can be used as aldehyde and amine reaction raw materials, condensation reaction with other compounds to generate compounds with biological activity.
4. Thermal stability: 2-amino -5-pyrimidine formaldehyde will decompose at high temperature, so it needs to be stored at low temperature.
the main uses of 2-amino -5-pyrimidine formaldehyde are as follows:
1. pharmaceutical field: as intermediates, for the synthesis of a series of bioactive compounds, such as antiviral drugs, anticancer drugs.
2. Chemical research: used for condensation and reduction reactions in organic synthesis reactions.
3. chromogenic agent: 2-amino -5-pyrimidine formaldehyde can form a dark complex with metal ions, which is used for the detection of metal ions in analytical chemistry.
2-amino -5-pyrimidine formaldehyde preparation method is more complex, generally can be synthesized by the following methods:
1. Starting from 2-amino -5-methyl pyrimidine, 2-amino -5-methyl pyrimidine -4-ol is first obtained by oxidation reaction.
2. Then the aldehyde reaction is carried out under the action of the oxidant to obtain 2-amino -5-pyrimidine formaldehyde.
During use and storage, you need to pay attention to the following safety information:
1. 2-Amino-5-pyrimidine formaldehyde has certain toxicity, contact with skin or inhalation of its vapor may cause irritation and injury.
2. during the operation should wear appropriate protective gloves, glasses and protective masks and other personal protective equipment, avoid direct contact or inhalation.
3. It should be operated in a well-ventilated environment and avoid contact with oxidants and combustibles to prevent dangerous reactions.
4.2-amino -5-pyrimidine formaldehyde should be stored in a sealed container, away from fire and heat sources, to avoid high temperature.
During use and handling, the relevant safety procedures should be strictly observed, and all applicable safety and environmental regulations should be followed.
Last Update:2024-04-09 21:21:28